Julien Rossignol received bachelor of science degrees in cellular biology and biochemistry from the University of Nantes, France. He received a master’s degree in molecular biology and biophysics from the University of Orleans, France and a Ph. D. in neuroscience from the University of Nantes, France. His graduate work involved studies on the therapeutic effect of adult stem cell transplantations in Huntington's disease rat model. Following post-doctoral fellowships at INSERM U643 in Nantes, France and in the Neuroscience Program and the Department of Psychology at Central Michigan University where he continued his work with stem cells as a potential cure for neurodegenerative diseases.
As a faculty member in the College of Medicine, I am conducting my research in the Field Neurosciences Institute Laboratory for Restorative Neurology.
My present laboratory research is to determine the best adult stem cell candidate to transplant in the brain to treat neurodegenerative diseases. His group studied specifically mesenchymal stem cells and induced pluripotent stem cells. Previous work has shown that mesenchymal stem cells slowed the deficits in a transgenic rat model of Huntington's disease but failed to create new neurons. Induced pluripotent stem cells have the ability to become neurons and may prove to have greater therapeutic utility.
In conjunction with the work on stem cells, research on nanoparticles and their advantages to deliver treatment are also studied particularly in stroke and glioblastoma.
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Lab website: https://www.cmich.edu/academics/colleges/college-of-medicine/research/basic/rossignol-lab/